Trimethoprim-sulphamethoxazole in Acute Osteomyelitis Due to Penicillin-resistant Staphylococci in Uganda

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منابع مشابه

Trimethoprim-sulphamethoxazole in acute osteomyelitis due to penicillin-resistant staphylococci in Uganda.

Most recent cases of staphylococcal osteomyelitis seen at Mulago Hospital, Kampala, have been due to penicillin-resistant organisms. Six severely ill patients-four with multiple bone lesions-were treated with trimethoprim-sulphamethoxazole; the response was prompt and satisfactory in all cases.

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In-vitro sensitivities were performed on 140 specimens of urine which grew Streptococcus faecalis of more than 100 000 organisms/ml between March 1970 and February 1971. Although the combination of trimethoprim and sulphamethoxazole definitely appeared to be more effective than sulphonamide alone and as effective as ampicillin, its use for more than two weeks in 14 cases of uncomplicated urinar...

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Penicillin is still satisfactory as the main treatment for gonorrhoea in Uganda, but there is evidence that its usefulness is declining. In 1961, there was a treatment failure rate of only 4 per cent. with a single dose of 0-3 mega units penicillin aluminium mono-stearate (PAM) (Kibukamusoke, 1965); four times that dose-1V2 mega units-gave a failure' rate of 17-9 per cent. in 1966 (Arya, unpubl...

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ژورنال

عنوان ژورنال: BMJ

سال: 1970

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.3.5716.201